Registration is still open for our 7th annual Little Giants Farm Run. The farm run is a great way to get outside and spend a fun-filled day with family and friends. Proceeds go towards The Little Giants Foundation to raise money for SIOD awareness and help fund research. Schimke Immuno Osseous Dysplasia is a rare, genetic, life-limiting disease that causes great suffering to the children who have it. Symptoms include vascular and kidney disease, a weakened immune system, and short stature caused by problems with skeletal growth.